基本信息

 

 

许林峰  博士  ｜ 教授  博士生导师

西安交通大学 青年拔尖学者计划入选者

西安交通大学-电信学部-自动化学院

 

 

Prof. Linfeng Xu, Ph.D.

School of Automation Science and Engineering

Xi'an Jiaotong University

 

 

工业及学术科研经历

  • 教授

西安交通大学

自动化学院

2023.01-

至今
  • 副研究员

加州大学旧金山分校

生物医学工程

2022.04-

2023.01
  • 博后

加州大学旧金山分校

生物医学工程

2018.05-

2022.03
  • 高级研究员

Intuitive Biosciences Inc.

研发部

2015.08-

2018.04
  • 研究员

Infinitesimal LLC

研发部

2015.01-

2015.07
  • 助教

纽约州立大学布法罗分校

电子工程

2010.08-

2014.12
  • 助研

纽约州立大学布法罗分校

电子工程

2010.08-

2014.12

联系方式

欢迎有兴趣的同学报考及咨询。

系统工程研究所

信息与生物医学交叉研究中心

（团队链接https://gr.xjtu.edu.cn/web/kaiye/research-group）

 

联系方式：

西安交大创新港校区4号巨构5058

邮箱：

xu.linfeng at xjtu.edu.cn

xu.linfeng at outlook.com

 

We are looking to recruit creative, idea-generating, and self-driven researchers. Our laboratory offers exceptional training across multiple disciplines, which is ideal for individuals who aspire to establish independent, research-focused careers in academia or industry. We adhere to a philosophy that advocates conducting top-notch scientific research by developing tools and methodologies to address critical biological inquiries that have significant real-world applications, using data produced within our lab. If you are enthusiastic about acquiring the mindset of a principal investigator, taking intellectual risks, and exploring uncharted territories in order to make significant advancements in knowledge and technology, we warmly encourage you to apply.

 

Lab: Room 5058, Building 4, Chuangxingang Campus

School of Automation Science and Engineering

Xi'an Jiaotong University

 

Email: xu.linfeng at xjtu.edu.cn

          xu.linfeng at outlook.com

 

我的新闻

站点计数器

研究领域

  • 基于微流控微液滴技术的新型超高通量生化医学检测工具

    • 现代大规模生化医学分析及筛选实验需要在降低成本的同时，大大提高检测精度与效率。针对这一难题，微流控技术特别是微液滴操控技术被视为最主要的解决方案之一。如何借助各种力学原理，设计主动或被动控制液体流动的微流控模块，如何对微量样本进行高通量精准检测及检测后如何高效分选是我研究的主要内容之一。

  • 单细胞水平代谢研究及多维组学分析

    • 开发并发展了针对单细胞代谢物研究的工作流程和新的分析方法；构建了基于质谱信号的高通量分选平台，并利用此平台对单细胞展开包含代谢组在内的多维组学研究。

  • 生物组织空间多维组学研究

    • 在单细胞分析的基础上，研发适用于大脑组织切片的空间多维组学方法，结合空间代谢组与转录组，从多维组学的角度系统分析由阿尔茨海默病引起的斑块是如何干扰邻近细胞的基因表达及表观特征。

近年以一作或通讯作者在Nature Communicaitons、Advanced Materials、Lab on a chip等期刊发表学术论文10多篇；申请美国及世界发明专利4项；留美期间科研转化初创公司一个；主持国家级科研项目1项、参与1项。

 

 

 

  • Novel engineering tools based on MICROFLUIDICS for biochemistry applications.
    • Handling a small volume of liquids at high precision and throughput is fundamental to large-scale biochemistry screening experiments. Since my Ph.D. study and throughout my academic career, I have designed, fabricated, and tested over 100 MEMS/Microfluidics devices. I am skilled in micropump design & integration for POC, micro-droplet manipulation either passively by structure or actively by electrical force, handling of various syringe pumps, thermal control for PCR, blood separation & micro-magnetic particle-based immunoassay and cell culture through microfluidic devices.
  • Exploring metabolism at the single-cell level
    • I initiated and developed the workflow and new analysis method for single-cell metabolites study employing droplet printing and MALDI-MS imaging to solve directed evolution issues in synthetic biology and multimodal omics study at the single-cell level.
  • Spatial Multimodal Omics
    • Continuing my interest in mass spectrometry and droplet microfluidics, I further developed my method for brain tissues at spatial and multimodal omics level to study how the plaque caused by Alzheimer’s disease interfere with neighboring cells.

 

方向一：微流控模块

 

方向二：高精度质谱与微流控结合

 

 

方向三：微流控质谱多组学分析耦联平台在生物酶定向进化上的示范应用