RES

• Novel engineering tools based on MICROFLUIDICS for biochemistry applications.
  • Handling a small volume of liquids at high precision and throughput is fundamental to large-scale biochemistry screening experiments. Since my Ph.D. study and throughout my academic career, I have designed, fabricated, and tested over 100 MEMS/Microfluidics devices. I am skilled in micropump design & integration for POC, micro-droplet manipulation either passively by structure or actively by electrical force, handling of various syringe pumps, thermal control for PCR, blood separation & micro-magnetic particle-based immunoassay and cell culture through microfluidic devices.
• Exploring metabolism at the single-cell level
  • I initiated and developed the workflow and new analysis method for single-cell metabolites study employing droplet printing and MALDI-MS imaging to solve directed evolution issues in synthetic biology and multimodal omics study at the single-cell level.
• Spatial Multimodal Omics
  • Continuing my interest in mass spectrometry and droplet microfluidics, I further developed my method for brain tissues at spatial and multimodal omics level to study how the plaque caused by Alzheimer’s disease interfere with neighboring cells.