Contact Information

Jie Han

Professor, Ph.D. (Auckland)
Department of Environmental Science and Engineering
Institute of Global Environmental Change
Xi’an Jiaotong University
Xi’an 710049, P.R. China
E-mail: jiehan (at) xjtu.edu.cn
Web: ​​​​​​​http://gr.xjtu.edu.cn/web/jiehan/home

Biography

I am a PI of the Environmental and Public Health (EPI) Research Group and a Professor at the Department of Environmental Science and Engineering at Xi’an Jiaotong University (XJTU). XJTU is a member of China’s C9 league and ranked among the top five in Science and Engineering in the country.

 

The overall theme of my research is on emerging contaminants, and much of my previous work was on the migration of trace organic compounds, into and out of, polymers including membranes, plastics, and elastomers. I have a strong interest in public health including risk identification, assessment, mitigation, and scientific communication to the public.

 

Prior to joining XJTU, I received research training and experience from the University of Auckland (UoA), National University of Singapore (NUS), University of Illinois at Urbana Champaign (UIUC), and University of Massachusetts Amherst (UMass Amherst), and worked with the PIs of several world-renowned laboratories in my fields. Since my Auckland times, I have supervised about 20 students, including several undergraduates who later developed strong interests in scientific research and pursued their PhDs. To date, I have delivered several research projects as the PI with about 3.5 million yuan in funding.

On COVID-19

To our fellow researchers, students, and prospective collaborators:​​​​​

 

I have always been working on emerging contaminants since the beginning of my PhD, and this virus, out of all the things I know, is the most dangerous ‘emerging contaminant’ threatening public health. I couldn't help but often staring at the rolling numbers and statistics thinking how many people are dying from this disease every day, every hour, and every moment, somewhere in this world. And we don't even know where it came from and how it got to this far.

 

I was born in the 80s, and have been through the 1998 flood, 2003 SARS, the Christchurch earthquake, etc. This is nothing like what I have seen. 

 

Since the beginning of my research career, I have been an experimental scientist. Every single project I did was an experimental study. I believe in science, and even more so in data. But now, I have a strong will to contribute, through commentaries, critical reviews, data analyses, new ideas, to voice our concerns and share our thoughts that could be useful to others in this pandemic. To me, the goal of saving lives through research has never been so real, and so urgent. If this doesn't motivate us, I don't know what will.

 

Medical researchers are racing against time, and so are we. The rolling numbers and daily mortality counts make us think that getting our best work out in a timely fashion is the most important thing for us to contribute on COVID-19. We have a dedicated 10-person team led by myself working day and night to ensure timely delivery and the scientific rigor of our work.

 

Viruses and pandemics are an essential part of the evolution process. Being the most intelligent species living on this planet, we humans have enjoyed far too many privileges by exploiting natural resources and other living species on this planet, for far too long. There is a time we must stop and think about how we could do better, live better, and get along better with other species living on earth, our only home. For now, there is nothing as urgent as understanding the origin, infection, and transmission of this virus in our communities, and for that we must stand together, research, and communicate using science as our most powerful tool to protect more people from dying from this pandemic.

 

We invite you to come back for further updates on our work. We update this page every 1-2 weeks to ensure the latest information is published here.

 

- Jie Han, at Xi'an Jiaotong University (2020.07.22)

Topics

Our current research covers the following domains:

 

(1) Tracing early infections and origins of novel pathogens

     (环境与早期感染溯源)

(2) Environmental transmission, vectors, and prevention

     (环境传播途径、传播介质与阻断)

(3) Human behavioral changes, environmental impact, and public health risks

     (人群行为变化及导致的环境效应与公众健康风险)

(4) Finding smarter cures, surveillance tools, disinfection methods, and preventive strategies

     (更有效的治疗、监测、消毒与预防策略)

(5) Decision-making and public health policies

     (决策与公共卫生政策制定)

 

We seek students, postdocs, and collaborators from microbiology, epidemiology, medical science, and public health related disciplines to conduct further work in these emerging research domains.

Publications & preprints (As of Feb 6, 2021)

Topic (1) Tracing early infections and origins of COVID-19

主题 (1) 环境与早期感染溯源

 

Discussion:

Biorepositories (biobanks) of human body fluids and materials as archives for tracing early infections of COVID-19. Environmental Pollution. https://www.sciencedirect.com/science/article/pii/S0269749121001032 (Submitted 3 October 2020; Published 18 January 2021)

(Preprint version) Biorepositories (biobanks) of human body fluids and materials as archives for tracing early infections of COVID-19. Available at SSRN.​​ http://dx.doi.org/10.2139/ssrn.3722520 (Date Written: 3 October 2020)

 (何珊珊 等.  利用“生物银行”中存档的人体体液与组织样本追溯早期新冠感染案例)

 

Top Ten papers on SSRN (60 days):

https://papers.ssrn.com/sol3/topten/topTenResults.cfm?groupingId=3068981&netorjrnl=jrnl (Civil & Environmental Engineering)
https://papers.ssrn.com/sol3/topten/topTenResults.cfm?groupingId=3069038&netorjrnl=jrnl (Health & Safety)
https://papers.ssrn.com/sol3/topten/topTenResults.cfm?groupingId=3068922&netorjrnl=jrnl (Bioengineering)

 

 

​​​​​​​Editorial:

(Preprint version) A dreadful loop: Can reverse zoonosis of COVID-19 seed unrestrained spread and mutations in wild species and transmission of novel strains to humans? Available at SSRN. http://dx.doi.org/10.2139/ssrn.3721791 (Date Written: 27 October 2020)​

Backward transmission of COVID-19 from humans to animals may propagate reinfections and induce vaccine failure. Environmental Chemistry Letters. https://doi.org/10.1007/s10311-020-01140-4 (Accepted 4 November 2020; Published 3 January 2021).​​​​​​​

(何珊珊 等.  大流行中人对动物的反向病毒输入,可能引发新冠病毒在野生动物中的无控传播与加速变异,导致新型毒株再次溢出至人类并降低疫苗有效性)

 

Top Ten papers on SSRN (60 days):

​​​​​​​https://papers.ssrn.com/sol3/topten/topTenResults.cfm?groupingId=3068981&netorjrnl=jrnl (Civil & Environmental Engineering)

https://papers.ssrn.com/sol3/topten/topTenResults.cfm?groupingId=3069038&netorjrnl=jrnl (Health & Safety)

https://papers.ssrn.com/sol3/topten/topTenResults.cfm?groupingId=3217680&netorjrnl=ntwk (Ecology)

 

【环境人Environmentor】公众号2020年11月6日 推送:西交大韩杰团队ECL: 大流行中人对动物的反向输入可能引发新冠病毒在野生物种中无控传播、变异与新型毒株溢出  原文链接:https://mp.weixin.qq.com/s/nwHfNLHKMDKzpXwXsJlvpg

​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​

2020年12月19日:论文预印本被Europe PubMed Central收录 https://europepmc.org/article/PPR/PPR241810

 

 

Topic (2) Environmental transmission, vectors, and mitigation

主题 (2) 环境传播途径、传播介质与预防

​​​​​​​

Review / Perspective:

Can the coronavirus disease be transmitted from food? A review of evidence, risks, policies and knowledge gaps. Environmental Chemistry Letters. https://doi.org/10.1007/s10311-020-01101-x (Published 1 October 2020; Submitted 3 September 2020)

 

(韩杰 张雪 等.  新冠病毒的食品传播:证据、风险、当前的政策与认知缺口)

 

【环境人Environmentor】公众号 2020年10月19日 推送:西交大韩杰团队ECL | 新冠病毒的食品传播:证据、风险、当前的政策与认知缺口  原文链接:https://mp.weixin.qq.com/s/1io6bkodSeOAscWdsOaU5A

 

根据施普林格(Springer)出版社的统计:该论文自2020年10月1日在线发表以来,总访问量已达到7201次 (Altmetric score: 272. Including: 735 tweeters, 71 Mendeley, 8 news outlets, 3 blogs, 1 Wikipedia page, 1 Facebook page) https://link.springer.com/article/10.1007%2Fs10311-020-01101-x/metrics​​​​​​​​​​​​​

 

Science 于2021年1月8日发表的题为"SARS-CoV-2 spillover events"的观点论文(Perspective),作者Peng Zhou与武汉病毒所石正丽 。论文中3处引用并用较大篇幅讨论了本文中的内容。Science论文链接: https://science.sciencemag.org/content/sci/371/6525/120.full.pdf 

 

 

Research Article:

Urban flooding events could pose risks of virus spread and community outbreaks during the coronavirus (COVID-19) pandemic. Science of the Total Environment. https://doi.org/10.1016/j.scitotenv.2020.142491 (Published 23 September 2020; Submitted 30 June 2020)

(韩杰 等.  疫情期间的城市洪灾导致新冠病毒传播与社区爆发的风险)

 

 

Editorial:

Breastfeeding in public amenities during the COVID-19 pandemic: Mothers and unprotected infantsEnvironmental Chemistry Letters. https://doi.org/10.1007/s10311-020-01054-1 (Published 21 July 2020)

(王雪 等.  疫情下的公共设施内哺乳:母亲与未受保护婴儿的暴露风险)

 

 

Correspondence:

Microfiber pillow as a potential harbor and environmental medium transmitting respiratory pathogens during the COVID-19 pandemicEcotoxicology and Environmental Safety. https://doi.org/10.1016/j.ecoenv.2020.111177 (Published 18 August 2020; Submitted 26 June 2020)

(韩杰 等.  纤维枕作为新冠病毒和其它呼吸道病原体的富集与传播介质)

 

报道: Lakshmi Supriya. Microfiber pillows could harbor SARS-CoV-2 particles (Sep 16, 2020) https://www.news-medical.net/news/20200916/Microfiber-pillows-could-harbor-SARS-CoV-2-particles.aspx

​​​​​​​

​​​​​​​​​​​​

Review / Perspective:

Open defecation and squat toilets, an overlooked risk of fecal transmission of COVID-19 and other pathogens in developing communitiesEnvironmental Chemistry Letters. https://doi.org/10.1007/s10311-020-01143-1 (Accepted 17 November 2020; Submitted 4 November 2020)

(孙世翼 等.  露天排便和蹲厕:发展中社区中被忽视的新冠及其它粪源病原体的传播风险) 

 

 

Review:

(Preprint version) The last inches: Human thermal plume as an overlooked factor in airborne transmission of COVID-19 in the human microenvironment. Available at SSRN. ​​​​​​http://dx.doi.org/10.2139/ssrn.3754655 (Date Written: December 8, 2020)

How human thermal plume influences near-human transport of respiratory droplets and airborne particles: a review​​​​. Environmental Chemistry Letters. https://doi.org/10.1007/s10311-020-01178-4 (Submitted 18 December 2020; Published 21 January 2021)

​​​​​(孙世翼 等. 人体微环境中的热羽流:新冠病毒空气传播过程中的一个被忽视的因素)​​​​

​​​​​​​​​

Top Ten papers on SSRN (60 days):
https://papers.ssrn.com/sol3/topten/topTenResults.cfm?groupingId=2929918&netorjrnl=jrnl (Transmission)
https://papers.ssrn.com/sol3/topten/topTenResults.cfm?groupingId=3385241&netorjrnl=ntwk (Nursing)​​​​

 

​​​​​​​​​​​​​​

Review:

(Preprint version) Invisible agents of COVID-19 transmission? Common sources, characteristics, and implications of indoor aerosols. Available at SSRNhttp://dx.doi.org/10.2139/ssrn.3752556 (Date Written: December 21, 2020)​​​​​​​​​​​​​​

Role of indoor aerosols for COVID-19 viral transmission: A review. Environmental Chemistry Letters. https://doi.org/10.1007/s10311-020-01174-8 (Submitted 18 December 2020; Published 13 January 2021)

​​​​​(陈博 等. 新冠病毒传播的隐形媒介?室内气溶胶的常见来源、特征及影响)​​​​​​​

 

 

Review / Perspective:

Electrostatic fine particles emitted from laser printers as potential vectors for airborne transmission of COVID-19Environmental Chemistry Letters. https://doi.org/10.1007/s10311-020-01069-8 (Published 7 August 2020; Submitted 21 July 2020)

 

 

(何珊珊 等.  激光打印机排放的静电细颗粒作为新冠病毒空气传播的潜在介质)

 

​​​​​​​

Topic (3) Human behavior changes, environmental impact, and associated health risks

主题 (3) 人群行为变化及导致的环境效应与公众健康风险

 

Discussion:

Need for assessing the inhalation of micro(nano)plastic debris shed from masks, respirators, and home-made face coverings during the COVID-19 pandemicEnvironmental Pollution. https://doi.org/10.1016/j.envpol.2020.115728 (Published 6 October 2020; Submitted 25 July 2020)​​​​​​​

(韩杰 等.  需研究疫情下人们从口罩与自制面罩中吸入微纳塑料颗粒的风险)​​​

​​​​​​​

根据美国化学会(ACS)统计:自8月2日论文上传至ChemAxiv预印本服务器以来,总访问量已达到5225次,下载次数299 https://chemrxiv.org/articles/preprint/Need_for_Assessing_the_Inhalation_of_Micro_nano_plastic_Debris_Shed_from_Masks_Respirators_and_Home-Made_Face_Coverings_During_the_COVID-19_Pandemic/12751718

 

 

Preprint:
Disinfectant- and antibiotic-resistance in community environments and risk of direct transfers to humans: Unintended consequences of community-wide surface disinfecting during COVID-19? Available at SSRN. https://ssrn.com/abstract=3778406 (Date Written: 7 December 2020)

(陈博 等. COVID-19疫情下广泛社区消毒加速滋生消毒剂与抗生素抗性及转移至人的风险)

 

【更新】On 29 January 2021, Nature published a Feature article (https://www.nature.com/articles/d41586-021-00251-4) where the author combed through existing evidence on fomite transmission of COVID-19 and raised questions over the cleaning and disinfection protocols that have been widely put in place in response to COVID-19. On the same day, two Australian scientists wrote a Letter to Science (https://science.sciencemag.org/content/371/6528/474.1.full) expressing concerns over the surging use of antimicrobials including disinfectants, sanitizers, and antiseptics during COVID-19, and warned on the potential of disinfectant-facilitated bacterial acquisition of antimicrobial resistance, a widely acknowledged environmental and public health risk. Our article, which was written on 7 December 2020 and currently under peer review, presents the first systematic view and in-depth analysis on this subject in the current literature context, by focusing on the chemical disinfecting agents currently approved for COVID-19 disinfection.

 

​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​

Perspective:
Locked on salt? Increased consumption of high sodium foods during COVID-19 presents an underappreciated public health risk. Available from SSRN. (Date Written: 10 January 2021)

(张雪 等. 疫情与居家令期间公众对高钠食品的摄入增加导致的健康风险)

 

 

Research Article:

To bin or to flush: Toilet paper presents a dilemma for developing communities during the COVID-19 pandemicEnvironmental Chemistry Letters. https://doi.org/10.1007/s10311-020-01064-z (Published 8 August 2020; Submitted 15 July 2020)

​​​​​​​

(孙世翼 等.  扔掉还是冲掉:疫情中发展中社区在厕纸丢弃方式上面临的两难)

 

 

Topic (4) Finding smarter cures, surveillance tools, disinfection and preventive strategies

主题 (4)  更有效的治疗、监测、消毒与预防策略

 

Research Article: 

Solar heating to inactivate thermal-sensitive pathogenic microorganisms in vehicles: Application to COVID-19. (Original title: Parking under the summer sun: A viable strategy for disinfecting COVID-19 in passenger vehicles​​​​​​​) Environmental Chemistry Letters https://doi.org/10.1007/s10311-020-01132-4 (Published 6 November 2020; Submitted: 15 October 2020)

(王雪 等.  阳光下泊车:太阳光照升温作为车内新冠病毒的一种被动灭活方式)

​​​​​​​​​​​​​​​​​​​​​

美国德特里克堡(Fort Detrick)生物实验室最近发表的一项follow-up study 中,引用并验证了本文的结论。作者用SARS-CoV-2真病毒,模拟阳光下车内密闭升温环境(气温54.5摄氏度、相对湿度20%、304不锈钢表面,3组重复),观察到新冠病毒在36分钟 (+/- 9分钟) 后,灭活率达到90%。​​​​​​​​​​​​​​

 

A follow-up study conducted at BNBI at Fort Detrick, United States, cited our findings and validated our conclusions in this paper. Authors used real SARS-CoV-2 isolates in their experiments simulating conditions in cabins of enclosed vehicles parked under direct sunlight  after a short period of time (i.e., 54.5 deg C, relative humidity 20%, on 304 stainless steel surfaces, in triplicate). The authors observed a 90% decrease in virus infectivity after 36 min (+/- 9 min). The results aligned well with our recommendation (20-30 min) based on our field measurements and data drawn on the thermal stability of SARS-CoV-2 available then.

​​​​​​​​​​​​​​

论文链接:Biryukov, J., Boydston, J.A., Dunning, R.A. et al. SARS-CoV-2 is rapidly inactivated at high temperature. Environ Chem Lett (2021). https://doi.org/10.1007/s10311-021-01187-x

 

 

​​​​​​​Editorial:

Who is running faster, the virus or the vaccine? (Original title: Vaccinating a global population for COVID-19: Unprecedented challenges call for innovative approaches and collaborative efforts) Environmental Chemistry Letters https://doi.org/10.1007/s10311-020-01110-w ​​(Published 15 October 2020)

​​​​​​​

(代寒 等.  为全球人口接种新冠疫苗:用创新的方法与协作应对前所未有的挑战)

 

​​​​​​​

Preprint: 

Beyond lockdowns, drugs and vaccines: Is there a smarter path to prepare our communities for novel pathogens? Available at SSRN. http://dx.doi.org/10.2139/ssrn.3741331 (Date Written: November 19, 2020)
​​​​​​​

(代寒 等. 跨越居家令、药物与疫苗:寻求一条应对人类新型病原体的更优途径)